Write the structures of fragments produced on complete hydrolysis of DNA. How are they linked in DNA molecule? Draw a diagram to show the pairing of nucleotide bases in double helix of DNA.
During the hydrolyses, the main constituents of DNA include a pentose sugar, nitrogenous bases and phosphoric acid
Attachment of base to I ‘-position of sugar results in formation of a nucleoside. The linkage of two nucleotides through phosphoric acid at 5′-position of sugar makes a nucleotide. Multiple nucleotides joined at 5’-and 3’carbon atoms of the pentose sugar by phosphodiester linkage makes a chain of nucleotides.
The coiling of two chains of nucleotides and held by the H-bond formation between bases makes DNA.