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  • (a) Describe the series of experiments of F. Griffith. Comment on the significance of the results obtained. (b) State the contribution of Macleod, McCarty and Avery.

(a) Describe the series of experiments of F. Griffith. Comment on the significance of the results obtained.

(b) State the contribution of Macleod, McCarty and Avery.

 

 

 

 
 
 
 
 

Answers (1)

(a) Streptococcus pnemoniane

     S- Strain injection into mice → mice die

    R - Strain injected into mice → mice alive

    S - Strain (heat killed) injected into mice → mice alive

    R - Strain (alive) + 5 (heat killed) strain inject into mice → mice die

As the R strain (non - virulent) picked up genetic material from S strain (virulent) and get transformed.

(b) They purified proteins DNA and RNA from heat killed S cells, they discovered protein digesting enzyme (protease) RNA digesting enzyme (RNAse) did not affect transformation, digestion with DNase inhibited transformation, conclued DNA is the hereidity material.

Posted by

Priyanka Kumari

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