Amphetamine effects are similar to cocaine. Amphetamines are the stimulants of the CNS ( central nervous system). Amphetamine increases the synaptic activity of dopamine and non - epinephrine neurotransmitter systems by releasing the dopamine from axon terminals, inhibiting the storage of dopamine in a vesicle or by destructing dopamine with the help of enzymes or by blocking the dopamine reuptake. All of these actions result in more dopamine in the synaptic cleft where it can act on receptors.
Short term effects of Amphetamine include increased heart - rate or blood pressure, reduced appetite, fatigue, dilation of pupils and long - term effects of amphetamine could result in insomnia , weight loss, hallucinations, violent and aggressive behavior.