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  • Stuck here, help me understand: If both parents are carriers for thalessemia, which isan autosomal recessive disorder, what arechances of pregnancy resulting in an affectedchild?

If both parents are carriers for thalessemia, which is an autosomal recessive disorder, what are chances of pregnancy resulting in an affected child?

  • Option 1)

    100%

  • Option 2)

    no chance

  • Option 3)

    50%

  • Option 4)

    25%

 

Answers (1)

best_answer

As we discussed in

 

Mendelian disorders -

These disorders are mainly determined by alteration or mutation in a single gene. Most common Mendelian disorders are Haemophilia, cystic fibrosis, Sickle cell, anaemia.

- wherein

 

The Mendelian disorders may be dominant or recessive.

 

 Thalassemia is the disorder due to reduced synthesis of either the alpha or beta chains, likewise designated as alpha or beta - thalassemias. When this autosomal mutant gene is present in a double dose. The disease is severely called as thalassemia major.


Option 1)

100%

Incorrect

Option 2)

no chance

Incorrect

Option 3)

50%

Incorrect

Option 4)

25%

Correct

Posted by

divya.saini

View full answer

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