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Which of the following is used for ascent of amine series?

Option: 1

Reduction of nitrile with LiAlH_4


Option: 2

Reduction with Sn + HCl 


Option: 3

Reduction with Fe + HCl 


Option: 4

Reduction with H_2 / Pd


Answers (1)

As we have learnt,

By Reduction of Nitriles and isocyanides 

Cyanide group is reduced to NH2  (1\degree\:Amine)  group by LiAIH4  or by catalytic hydrogenation. 

R-C=N\overset{LiAIH_{4}}{\rightarrow} RCH_{2}-NH_{2}

Ascent of amine series means the preparation of amines containing one carbon atom more than the starting amine.

Posted by

Sumit Saini

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