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Assertion: The capture of energy generated during glucose oxidation via hexose monophosphate shunt is as efficient as the glycolytic-Krebs cycle pathway

Reason (R): The synthesis of 36 molecules of ATP can be achieved by forming 12 molecules of reduced NADP via hexose monophosphate shunt.

 

Option: 1

Both A and R are true and R is the correct explanation of A.


Option: 2

Both A and R are true but R is not the correct explanation of A.


Option: 3

A is true but R is false.


Option: 4

A is false but R is true.

 


Option: 5

Both A and R are false.


Answers (1)

best_answer

6-phosphogluconic acid and ribulose-5-R synthesis processes result in reduced NADP. There would be 12 molecules of reduced NADP formed if the equivalent of one glucose molecule is to be oxidized by this cyclic pathway (six cycles). 

The hydrogens from NADPH can be transferred to NAD to produce NADH in the presence of the enzyme transhydrogenase.

Therefore, the synthesis of 36 molecules of ATP can result from the formation of 12 molecules of reduced NADP via hexose monophosphate shunt. 

As a result, the glycolytic-Krebs cycle pathway and hexose monophosphate shunt are both equally effective at capturing the energy generated during the oxidation of glucose.

Option 1 is the correct answer.

Posted by

Pankaj

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