Consider the following four statements (i-iv) regarding kidney transplant and select the two correct ones out of these.
(i) Even if a kidney transplant is proper the recipient may need to take immune suppresants for a long time
(ii) The cell mediated immune response is responsible for the graft rejection
(iii) The B lymphocytes are responsible for rejection of the graft
(iv) The acceptance or rejection of a kidney transplant depends on specific interferons
The two correct statements are:
(ii) and (iii)
(iii) and (iv)
(i) and (iii)
(i) and (ii)
A kidney transplant is an allogeneic transplant. Since no two people, except identical twins, have the same HLA alleles or MHC proteins, the person will need immunosuppressive drugs, such as cyclosporine, throughout their life.The cell-mediated immune response, or T cell-mediated immunity, is responsible for graft rejection, not B cells. Hence, option 4 is correct.