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Determine the accurate statements regarding the process of the sliding filament theory governing muscle contraction:
Statement 1: The attachment of the myosin tail to the actin filament is a crucial step.
Statement 2: The myosin detachment from the actin filament coincides with the binding of a fresh ATP molecule.
Statement 3: An elevated concentration of Ca2+ contributes to the exposure of the myosin-binding sites to actin.
Statement 4: Upon binding actin, myosin undergoes ATP hydrolysis, utilizing the resultant energy to draw the actin filament inward towards the sarcomere's center.
Statements 1 and 2 are correct.
Statements 2 and 3 are correct.
Statements 3 and 4 are correct.
Statements 1 and 4 are correct
Answers (1)
In the sliding filament theory of muscle contraction, statement 2 accurately states that myosin detaches from the actin filament when a new ATP molecule binds. This detachment allows for the release of the actin filament and prepares myosin for the next cycle of muscle contraction.
Statement 3 is also correct, as an increased concentration of Ca2+ is essential for exposing the myosin-binding sites to actin. The presence of Ca2+ triggers a series of events that lead to the interaction between myosin and actin, initiating muscle contraction. Therefore, Option 2 is the correct answer.
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