During cell cycle in human beings , the formation of chromosome occurs at
Metaphase stage
Prophase stage
Anaphase stage
Telophase stage
As we have learned
Chromosomes -
The 'beads-on-string' in chromatin is packaged to form chromatin fibres that are further coiled and condensed at metaphase stage of cell division to form chromosomes.
- wherein
The packaging of chromatin at higher level requires additional set of proteins that is referred to as Non-Histone Chromosomal (NHC) protein.