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During glycolysis, which enzyme converts glucose-6-phosphate into fructose-6-phosphate?

 

Option: 1

Hexokinase


Option: 2

Isomerase


Option: 3

Phosphofructokinase

 


Option: 4

Aldolase


Answers (1)

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During the second step of glycolysis, an isomerase enzyme converts Glucose-6-phosphate into Fructose-6-phosphate. Isomerases are enzymes that catalyze the conversion of a molecule into its isomer, which has the same chemical formula but a different structural arrangement.

Hexokinase (option 1) is incorrect because it catalyzes the phosphorylation of glucose, not the conversion of glucose-6-phosphate into fructose-6-phosphate.

Phosphofructokinase (option 3) is incorrect because it is responsible for the phosphorylation of fructose-6-phosphate into fructose-1,6-bisphosphate.

Aldolase (option 4)  is incorrect because it leaves fructose-1,6-bisphosphate in two three-carbon isomers.

Therefore, the correct answer is option 2  - Isomerase. 

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