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If fatty acids were to be respired they would first be degraded to acetyl CoA and enter the pathway. This process of degradation of fatty acids into acetyl Co-A is called

Option: 1

Beta-oxidation of fatty acids


Option: 2

Gluconeogenesis


Option: 3

Alpha-oxidation of fats


Option: 4

Both a and c


Answers (1)

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Amphibolic Pathway -

  • Glucose is the favoured substrate for respiration. All carbohydrates are usually first converted into glucose before they are used for respiration.
  • Other substrates can also be respired, but then they do not enter the respiratory pathway at the first step.
  •  Fats would need to be broken down into glycerol and fatty acids first. If fatty acids were to be respired they would first be degraded to acetyl CoA and enter the pathway. This is called beta-oxidation of fats.
  • Glycerol would enter the pathway after being converted to PGAL.
  • The proteins would be degraded by proteases and the individual amino acids (after deamination) depending on their structure would enter the pathway at some stage within the Krebs’ cycle or even as pyruvate or acetyl CoA.
  • Since respiration involves the breakdown of substrates, the respiratory process has traditionally been considered a catabolic process and the respiratory pathway as a catabolic pathway.
  • But the intermediates of the Krebs’ cycle are used for anabolic processes.

 

Posted by

Suraj Bhandari

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