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In mouse agouti locus is hypostatic to pigment development locus. If C is for pigment development, and A is for agouti, and recessive alleles in agouti locus gives black colour and recessive in pigment locus gives white colour, what will be the phenotype of A/- c/c and a/a c/c.
 

Option: 1

Agouti, White 
 


Option: 2

Black , agouti 
 


Option: 3

Only black
 


Option: 4

Only white 
 


Answers (1)

best_answer

 

 

As we have already studied in Supplementary gene interaction or recessive epistasis -

Recessive epistasis is pigmentation in mice which is controlled by two pairs of genes A/a and C/c.

  • Dominant C produces black color when gene A/a is recessive homozygous.
  • When gene A is homozygous recessive or heterozygous with gene C/c, agouti is produced.
  • However, when gene C/c is homozygous recessive, it masks the formation of any color and albino/white coat is produced.
  • Therefore, gene C/c is being epistatic in recessive homozygous conditions.
  • This happens because a mouse with a recessive c allele at this locus is unable to produce pigment and is albino regardless of the allele present at locus A.

Hence, the correct option is (d).

Posted by

Nehul

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