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Read the following statements and select the correct option.
Statement 1: Malarial parasite requires two hosts - humans and mosquitoes to complete its life cycle.
Statement 2: Haemozoin is a toxic substance produced by the rupturing of liver cells during malarial infection
Both statements 1 and 2 are correct
Statement 1 is correct and statement 2 is incorrect.
Statement 1 is incorrect but statement 2 is correct.
Both statements 1 and 2 are incorrect
Answers (1)
In malaria, the malarial parasite (Plasmodium) undergoes a complex life cycle that involves two hosts - humans and mosquitoes. This is stated correctly in Statement 1. The parasite's life cycle begins when an infected female Anopheles mosquito bites a human and injects the parasite into the bloodstream. Inside the human host, the parasite multiplies and causes the characteristic symptoms of malaria.
Statement 2 states that hemozoin is a toxic substance produced by the rupturing of liver cells during a malarial infection. This statement is incorrect. Haemozoin is actually a byproduct of the parasite's digestion of hemoglobin in red blood cells, not liver cells. When the parasite consumes hemoglobin, it releases waste products, including hemozoin, which forms crystalline structures. These structures are not toxic to the liver cells but are recognized by the immune system, contributing to the immune response against the parasite.
Therefore, Statement 1 is correct and Statement 2 is incorrect. Hence, the correct answer is option 2.
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