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  • Reduction in pH of blood will:Option: 1 reduce the rate of heart beat.<div class='qna-option'

Reduction in pH of blood will:

Option: 1

reduce the rate of heart beat.


Option: 2

reduce the blood supply to the brain.


Option: 3

decrease the affinity of hemoglobin with oxygen.


Option: 4

release bicarbonate ions by the liver.


Answers (1)

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Oxygen Transport and Oxygen Dissociation Curve -

  • Blood is the medium of transport for O_{_{2}} and CO_{_{2}}. 
  • About 97 percent of O_{_{2}} is transported by RBCs in the blood. 
  • The remaining 3 percent of O_{_{2}} is carried in a dissolved state through the plasma. 
  • Haemoglobin is a red coloured iron-containing pigment present in the RBCs. 
  • O_{_{2}} can bind with haemoglobin in a reversible manner to form oxyhaemoglobin. This is called O2-Hb association.
  • Each haemoglobin molecule can carry a maximum of four molecules of O_{_{2}}.
  • Binding of oxygen with haemoglobin is primarily related to the partial pressure of O_{_{2}}.

As we learnt in 

Oxygen Dissociation Curve -

A sigmoid curve is obtained when percentage saturation of haemoglobin with O2 is plotted against the p_{O_{2}}. This curve is called the Oxygen dissociation curve and is highly useful in studying the effect of factors like p_{CO_{2}}, H+ concentration, etc., on binding of O2 with haemoglobin.

- wherein

 High concentration of H+ will reduce the pH, which will decrease the affinity of Hb with O_{2}  .

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shivangi.shekhar

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