Which of the following process is used in the conversion of pyruvate to acetyl CoA in mitochondrial matrix?
Oxidative decarboxylation
Oxidative dehydrogenation
Oxidative dehydration
Oxidative phosphorylation
Oxidative decarboxylation -
In mitochondria matrix pyruvate is decarboxylated and dehydrogenated. The 2 carbon product reacts with sulphur containing coenzyme A to form acetyl CoA
- wherein
Pyruvate + NAD+ + CoA Acetyl CoA + NADH + H+ + Co2