The endoplasmic reticulum (ER) and the bodies connected with it separate out as a fraction during the process of ultracentrifugation. The separated fraction is known as:
Ribosome
Polysome
Lysosome
Microsome
Option 4 is correct because the endoplasmic reticulum and the bodies connected with it are together called microsomes which separate out as a fraction during ultracentrifugation. The broken pieces of ER together with attached ribosomes are the microsomes. Microsome is obtained after the cell contents undergo ultracentrifugation. The separated fraction actually includes various organelles such as Golgi bodies, endoplasmic reticulum, etc.
Explanation for the incorrect options :
Option 1 is incorrect because the separated fraction during ultracentrifugation is called microsome. Ribosomes are not called microsomes but the broken pieces of ER together with attached ribosomes are called microsomes.
Option 2 is incorrect because the separated fraction is not known as polysome. Polysomes are a set of ribosomes that are attached to mRNA molecules just like beads on a thread.
Option 3 is incorrect because the separated fraction is not called lysosomes. They are called microsomes. Microsomes resemble lysosomes in size and are filled with enzymes just like lysosomes.