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The following statements are related to oxidative phosphorylation.
P. Redox reactions of electron transport chains coupled with AlP synthesis are collectively called oxidative phosphorylation.
Q. Three major processes: glycolysis, oxidative pentose phosphate pathway and citric acid cycle are related to oxidative phosphorylation.
R. Electron transport proteins are bound to the outer of the two mitochondrial membranes.
S. In the electron transport chain electrons are transferred to oxygen from NADH.
Which one of the following combinations of the above statements is correct?
P and S
Q and R
R and S
P and R
Answers (1)
The three major processes mentioned—glycolysis, oxidative pentose phosphate pathway, and citric acid cycle—are related to cellular respiration, but specifically to the production of ATP through substrate-level phosphorylation. Oxidative phosphorylation, on the other hand, refers to the process of ATP synthesis in mitochondria through the electron transport chain (ETC) and ATP synthase.
The ETC and ATP synthase are associated with the inner mitochondrial membrane, not the outer membrane. The electron transport proteins, such as cytochromes and flavoproteins, are embedded within the inner mitochondrial membrane. It is across this membrane that the electron transport chain occurs, leading to the establishment of a proton gradient that drives ATP synthesis by ATP synthase, which is also located in the inner mitochondrial membrane.
In summary, the major processes of glycolysis, oxidative pentose phosphate pathway, and citric acid cycle are related to cellular respiration but not directly to oxidative phosphorylation. Additionally, the electron transport proteins involved in oxidative phosphorylation are associated with the inner mitochondrial membrane, not the outer membrane. Hence, the correct answer is option 1.
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