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The inhibition of Succinic dehydrogenase by malonate is an example of 

Option: 1

Competitive inhibition

Option: 2

Non competitive inhibition

Option: 3

Allosteric inhibition

Option: 4

Competitive and Allosteric inhibition

Answers (1)


Succinic dehydrogenase is an enzyme that catalyzes the oxidation of succinate to fumarate in the tricarboxylic acid (TCA) cycle. Malonate is a structural analogue of succinate, meaning that it has a similar shape and can bind to the active site of the enzyme. However, malonate cannot be catalyzed by succinic dehydrogenase, and once it binds to the active site, it prevents succinate from binding and being catalyzed. This type of inhibition is known as competitive inhibition.

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Gautam harsolia

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