The process by which the mammary gland undergoes involution, returning to its non-lactating state, is primarily regulated by the hormone:
Estrogen
Progesterone
Prolactin
Human placental lactogen (hPL)
The process by which the mammary gland undergoes involution, returning to its non-lactating state, is primarily regulated by the hormone progesterone.
During pregnancy, progesterone plays a crucial role in preparing the mammary gland for milk production and maintaining the structure of the alveoli, which are the milk-secreting units within the gland. Progesterone works in conjunction with other hormones, such as estrogen and prolactin, to stimulate the growth and development of the mammary gland.
After childbirth, when lactation is no longer needed, progesterone levels decline. The decrease in progesterone signals the initiation of involution, which is the process of the mammary gland returning to its non-lactating state. During involution, the glandular tissue regresses, and the alveoli undergo remodeling.Hence, the correct answer is option 2.