Q.116) The protein portion of an enzyme is called:
A) Prosthetic group
B) Cofactor
C) Coenzyme
D) Apoenzyme
Q.116) Apoenzyme is the protein portion of an enzyme that is inactive on its own.
It requires a non-protein component (cofactor or coenzyme) to become an active enzyme, called a holoenzyme.
Let’s look at the other options:
(1) Prosthetic group – A tightly bound, non-protein part of an enzyme (often organic) essential for activity.
(2) Cofactor – A general term for non-protein helpers, can be metal ions or organic molecules.
(3) Coenzyme – A loosely bound organic cofactor, often derived from vitamins.
Hence, the correct answer is option (4): Apoenzyme.