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What is the Barr body?

 

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A Barr body is an inactive X chromosome found in the nucleus of female mammalian cells. It is only found in females (XX), since males (XY) have only one X chromosome. They form to balance gene expression between males and females and occur during early embryonic development, confirming that only one X chromosome remains active.

The number of Barr bodies in a cell is = Total X chromosomes – 1.

Example:

  • Normal Female (XX) → 1 Barr body
  • Turner Syndrome (XO) → 0 Barr bodies
  • Klinefelter Syndrome (XXY) → 1 Barr body
Posted by

Saniya Khatri

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