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Which of the following liver diseases occur due to reduced ATP generation?

Option: 1


Option: 2

Hypertrophic cardiomyopathy

Option: 3

3-Methylglutaconic aciduria


Option: 4

Lactic acidosis

Answers (1)


Most cases present due to isolated ATP synthase deficiency are neonatal-onset hypotonia, lactic acidosis, hyperammonemia, hypertrophic cardiomyopathy, and 3-methylglutaconic aciduria.

Damage to liver cells has several effects because the majority of activities take place primarily in the liver. 

Hyperammonemia, which results in convulsions and coma in liver disorders. 

This is caused by a decrease in the amount of ATP produced as a result of the removal of -ketoglutarate and the production of glutamate, which then produces glutamine.

Option 1 is the correct answer. 

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