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Which of the following process is regulated by spindle checkpoint?

Option: 1

Chromosome replication

Option: 2

Chromosome segregation

Option: 3

Spindle formation

Option: 4

None of the above

Answers (1)


B. The spindle checkpoint, sometimes referred to as the mitotic checkpoint, is a control mechanism that makes sure the chromosomes are properly segregated during cell division. The spindle checkpoint keeps track of how chromosomes are connected to spindle microtubules and postpones the start of anaphase until every chromosome is properly attached and positioned at the metaphase plate. Hence option B is correct.

A. The spindle checkpoint does not control the replication of the chromosomes, which takes place during the S-phase of the cell cycle. Hence option A is incorrect.

C. Although spindle formation is a crucial process that happens during cell division, the spindle checkpoint does not directly control it. Other systems, including as the centrosome duplication cycle, microtubule polymerization, and motor proteins, control spindle development. Hence option C is incorrect.

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