Q.128) Why can't insulin be given orally to diabetic patients? (1) Its bioavailability will be increased (2) Human body will elieit strong immune response (3) It will be digested in Gastro-Intestinal (GI) tract (4) Because of structural variation
A) Its bioavailability will be increased
B) Human body will elieit strong immune response
C) It will be digested in Gastro-Intestinal (GI) tract
D) Because of structural variation
Insulin is a protein hormone. If taken orally, it gets broken down by digestive enzymes in the stomach and intestine just like any other protein, so it won’t reach the bloodstream or have its intended effect on blood sugar. That’s why insulin is usually given by injection.
Hence, option(3) is correct.