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6. Using a Punnett Square, workout the distribution of phenotypic features in the first filial generation after a cross between a homozygous female and a heterozygous male for a single locus.

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In guinea pigs, homozygous female with white coat colour (bb) is cross with the heterozygous male having black coat colour (Bb). The male gamete will produce two types of gametes i.e. B and b while female will produce only one type of gamete which is b. The F1 progeny will show both individuals with black coat colour and white coat colour in a ratio of 1:1. Here, the phenotypic, as well as the genotypic ratio, will be 1:1. 

Parents(male/female)      Bb                       bb

Gametes                      B         b                    b         

Crossing                                        Bb     :       bb

                                   Black coat colour :  White coat colour        

Genotypic ratio- Bb:bb 1:1

Phenotypic ratio- Black coat colour : white coat colour 1:1   

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Sonika

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