Which technique among the following, is most appropriate in separation of a mixture of of
-nitrophenol and picric acid ?
Steam distillation
2-5 ft long column of silica gel
Sublimation
Preparative TLC (Thin Layer Chromatography)
The method that can be used for separation for 100 mg mixture of picric acid and p-nitrophenal is TLC (Thin layer Chromatography) using a appropriate salvent. Since the retention factor is different for both hence can to reparated.
Hence, Option (4) is correct.
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