Assertion: DNA ligase is responsible for joining the Okazaki fragments during DNA replication.
Reason: DNA ligase catalyzes the formation of a phosphodiester bond between adjacent nucleotides to form a covalent bond between the sugar and phosphate groups of the DNA backbone.
Both assertion and reason are true, and the reason is the correct explanation of the assertion.
Both assertion and reason are true, but the reason is not the correct explanation of the assertion.
The assertion is true, but the reason is false.
The assertion is false, but the reason is true.
The Assertion is true, as DNA ligase is responsible for joining the Okazaki fragments (short DNA fragments synthesized on the lagging strand during DNA replication) by catalyzing the formation of a phosphodiester bond between adjacent nucleotides. The Reason is also true, as this is the primary mechanism by which DNA ligase forms covalent bonds between adjacent nucleotides in the DNA backbone.
Option 1 is the correct answer.