Assertion: Topoisomerase is required for relieving the supercoiling tension in DNA during replication.
Reason: Topoisomerase cuts the DNA strands and re-joins them to relieve the supercoiling tension caused by the unwinding of the double helix during DNA replication.
Both assertion and reason are true, and the reason is the correct explanation of the assertion.
Both assertion and reason are true, but the reason is not the correct explanation of the assertion.
The assertion is true, but the reason is false.
The assertion is false, but the reason is true.
The Assertion is true, as topoisomerase is responsible for relieving the supercoiling tension that arises during DNA replication. It does this by cutting the DNA strands and re-joining them in a relaxed state. The Reason is also true, as this is the mechanism by which topoisomerase works to relieve the supercoiling tension.
Option 1 is the correct answer.