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Conformational change in DNA by UV  rays is caused due to 
 

Option: 1

Replication inhibition
 


Option: 2

Thymine dimer formation 
 


Option: 3

Unwinding of DNA strand 
 


Option: 4

All of the above 
 


Answers (1)

best_answer

 

 

 

 

As we have already discussed in mutagenesis & mutagens -

  • Mutagenesis is the process of inducing mutations through a number of physical, chemical or biological agents.
  • The agents that cause mutations are called mutagens.

Types of Mutagens:

  • Physical Mutagens:
    • X-rays, gamma rays and cosmic rays are ionizing radiation.
    • They ionize the water of the cells to release free hydroxyl radicals.
    • The hydroxyl radical is a powerful oxidizing agent. It oxidizes the phosphodiester bond of DNA and induces mutations.
    • It can cause break in one or both the strands of DNA; loss of section of chromosome and fatality if remain unrepaired.
    • UV rays are non-ionizing radiation. These induce the formation of thymine dimer.
    • Formation of thymine dimer changes conformation of DNA.

 

 
 Hence, the correct option is (b).

 

 

Posted by

Pankaj Sanodiya

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