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Consider the following assertion and reason statements. Choose the correct option based on their correctness and the explanation provided.
Assertion(A) - Due to its hydrophilic nature, DNA cannot pass through the cell membrane.
Reason (R) - Electroporation creates transient microscopic pores in the cell membrane, facilitating the entry of DNA molecules into the cell.
Option: 1
Both the A and R are correct, and the R explains the A.
Option: 2
Both theA and R are incorrect.
Option: 3
The A is correct, but the R is incorrect.
Option: 4
The A is incorrect, but the Ris correct.
Answers (1)
- Assertion states that due to its hydrophilic nature, DNA cannot pass through the cell membrane. This is correct because the cell membrane is primarily composed of a lipid bilayer which is hydrophobic, meaning it repels water and hydrophilic molecules like DNA.
- Reason states that electroporation creates transient microscopic pores in the cell membrane, facilitating the entry of DNA molecules into the cell. This is also correct because electroporation is a technique that uses electrical pulses to create temporary pores or openings in the cell membrane. These pores allow the passage of molecules, including DNA, into the cell that would otherwise be hindered by the hydrophobic nature of the membrane.
- Furthermore, the reason (R) explains the assertion (A) by providing a mechanism through which DNA can overcome its hydrophilic nature and enter the cell.
- Therefore, the correct answer is an option (1) - Both the assertion (A) and reason (R) are correct, and the reason explains the assertion.
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