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Haemolytic disease of the newborn occurs due to passage of ____ in the foetus through the mother’s blood. Choose the correct option to fill in the blank

 

Option: 1

Anti Rh antibodies

 

 

 


Option: 2

Rh antigens

 


Option: 3

ABO antibodies

 


Option: 4

None of the above


Answers (1)

best_answer

 

 

 

Rh incompatibility During pregnancy

  • During pregnancy, Rh incompatibility is seen when the father’s blood is Rh+ while the mother’s blood is Rh-. 
  • Therefore, if a father’s blood is Rh+ and the mother’s blood is Rh-, the blood of their baby will be Rh+ ( Rh+ is dominant over Rh- ). 
  • In such interaction, generally, the first child does not suffer, however, the subsequent foetuses do
  • In the subsequent foetuses, anti-Rh factors of mothers blood attack and destroy the RBCs of foetus. This leads to haemolytic disease of the newborn or HDN
  • This condition is called erythroblastosis foetalis.
  • The newborns that survive are anaemic 
  • To prevent HDN, Rh- mothers are injected with a defective anti-Rh-antibody during all pregnancies carrying Rh+ foetus. Marriage between Rh- woman and Rh+ man is not recommended. 

 

Hence, the correct answer is option a.

 

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Nehul

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