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In gene therapy of Adeosine Deaminase (ADA) deficiency, the patient requires periodic infusion of genetically engineered lymphocytes because:

Option: 1

Gene isolated from marrow cells producing ADA is introduced into cells at embryonic stages.


Option: 2

Lymphocytes from patient's blood are grown in culture outside the body


Option: 3

Genetically engineered lymphocytes are not immortal cells.


Option: 4

Retroviral vector is introduced into these lymphocytes.


Answers (1)

best_answer

In ADA deficiency, lymphocytes are given but these cells are immortal and hence periodic infusion is needed. Option 2 is correct. 

Posted by

Rakesh

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