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  • Read the following statements: 1. The transforming principle was characterized as DNA by Griffith. 2. Oswald Avery, Colin MacLeod and Maclyn McCarty decoded the nature of transforming

Read the following statements:
1. The transforming principle was characterized as DNA by Griffith.
2. Oswald Avery, Colin MacLeod and Maclyn McCarty decoded the nature of transforming principle in Griffith’s experiment.
3. Protein-digesting enzymes (proteases) and RNA-digesting enzymes (RNases) resulted in transformation.
4. DNA-digesting enzyme (DNase) caused inhibition of transformation, which suggests that the DNA caused the transformation. 
Select the correct option:
 

Option: 1

1, 2 and 4
 


Option: 2

2, 3 and 4
 


Option: 3

2 and 4
 


Option: 4

1 and 4
 


Answers (1)

best_answer

 

 

As we have already discussed in Biochemical Characterisation of Transforming Principle -

 

Oswald Avery, Colin MacLeod and Maclyn McCarty (1933-44) worked to determine the biochemical nature of ‘transforming principle’ in Griffith’s experiment in an in vitro system. The DNA-digesting enzyme (DNase) caused inhibition of transformation, which suggests that the DNA caused the transformation. 
Hence, the correct option is (c).

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