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The major contractile proteins of muscles are
Option: 1
Actin
Option: 2
Myosin
Option: 3
Both a and b
Option: 4
Albumin
Answers (1)
Structure of Contractile Proteins -
Actin Filament:
- Each actin (thin) filament is made of two ‘F’ (filamentous) actins helically wound to each other.
- Each ‘F’ actin is a polymer of monomeric ‘G’ (Globular) actins.
- Two filaments of another protein, tropomyosin also run close to the ‘F’ actins throughout its length.
- A complex protein Troponin is distributed at regular intervals on the tropomyosin (which bears actin-binding sites)
- In the resting state a subunit of troponin masks the active binding sites for myosin on the actin filaments.
Myosin Filament:
- Each myosin (thick) filament is also a polymerised protein.
- Many monomeric proteins called Meromyosins constitute one thick filament.
- Each meromyosin has two important parts, a globular head with a short arm and a tail, the former being called the heavy meromyosin (HMM) and the latter, the light meromyosin (LMM).
- The HMM component, i.e.; the head and short arm projects outwards at a regular distance and angle from each other from the surface of a polymerised myosin filament and is known as a cross arm.
- The globular head is an active ATPase enzyme and has binding sites for ATP and active sites for actin.
-
actin and myosin are two contractile proteins of muscles. Hence the correct option is c. both a and b
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