What is the function of renin in the body?
Stimulates bone marrow to increase RBC production
Converts angiotensinogen to angiotensin I
Increases blood pressure and enhances blood flow
Promotes absorption of calcium and phosphorus in the small intestine
Renin is an enzyme that plays a crucial role in regulating blood pressure and fluid balance in the body. When the rate of ultrafiltration in the kidneys decreases, the cells of the juxtaglomerular complex release renin into the bloodstream.
Renin acts upon a protein called angiotensinogen, which is produced by the liver, and converts it into angiotensin I. Angiotensin I is then further converted to angiotensin II by an enzyme called angiotensin-converting enzyme (ACE), primarily found in the lungs.
Angiotensin II is a potent vasoconstrictor, meaning it causes the blood vessels to constrict or narrow. This constriction increases resistance to blood flow and raises blood pressure. Angiotensin II also stimulates the release of aldosterone, a hormone that acts on the kidneys to increase sodium reabsorption and water retention, further contributing to an increase in blood pressure.
Therefore, the function of renin in the body is to initiate a cascade of events that ultimately lead to an increase in blood pressure and enhanced blood flow.
Option 3 is the correct answer.