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When subjected to electrophoresis, how would the mobility of hemoglobin (Hb) differ between a healthy individual and a sickle-cell patient, thereby reflecting their distinct hemoglobin variants, with options indicating:
Identical mobilities of Hb in both individuals
Divergent mobilities of Hb between the individuals
Complete immobility of the sickle-cell patient's Hb
Hb variants displaying no mobility during electrophoresis
Answers (1)
Option 2 states that the mobility of hemoglobin (Hb) would differ between a healthy individual and a sickle-cell patient when subjected to electrophoresis. This implies that the hemoglobin variants present in the two individuals have different electric charges or molecular structures, resulting in distinct migration patterns during electrophoresis. By observing the differential mobilities, it is possible to differentiate between the normal Hb found in a healthy individual and the altered Hb characteristic of a sickle-cell patient.
Hence, the correct answer is option 2.
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