Which of the following is responsible for the packaging of DNA into chromatin?
Histones
DNA polymerase
RNA polymerase
Ligase
Histones are proteins that help package DNA into chromatin by wrapping the DNA around them to form nucleosomes. The formation of chromatin through histone-DNA interactions plays an important role in gene regulation, as the compact structure of chromatin can affect the accessibility of DNA to transcription factors and other proteins. Chromatin remodeling complexes can change the position of nucleosomes along the DNA, thereby regulating gene expression. Hence option 1 is the correct answer.