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C-peptide of human Insulin is:

a. A part of mature insulin molecule
b. Responsible for formation of disulphide bridges
c. Removed during maturation of pro-insulin to insulin
d. Responsible for its biological activity

Answers (1)

c) Removed during maturation of pro-insulin to insulin

The connecting peptide or C-peptide is a short protein containing 31 amino acids. It connects the A and B chains of proinsulin molecules. After the processing of the proinsulin molecule, the C-peptide is removed leaving behind A and B chains which are bound together by disulphide bonds to constitute an insulin molecule. 

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Priyanka Kumari

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