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  • Gene therapy is an attempt to correct a genetic defect by providing a normal gene into the individual. By this, the normal function can be restored.

Gene therapy is an attempt to correct a genetic defect by providing a normal gene into the individual. By this, the normal function can be restored. An alternate method would be to provide the gene product (protein/enzyme) known as enzyme replacement therapy, which would also restore the function. Which is your opinion is a better option? Give a reason for your answer.

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Enzyme replacement therapy works on artificially administering the required enzyme into the patient’s body. This helps in the management of the disease. However, this needs frequent re-administration of enzyme and other necessary drugs to continue the therapy. In most of the cases, the therapy is costly and is a cause of financial and emotional drain on the patient. Using gene correction is a permanent solution. For example, a person with ADA deficiency can be permanently cured if the required gene is introduced during the embryo stage. This will ensure a better quality of life for the patient.

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Gurleen Kaur

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