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The role of DNA ligase in the construction of a recombinant DNAmolecule is:
a. Formation of a phosphodiester bond between two DNA fragments
b. Formation of hydrogen bonds between sticky ends of DNA fragments
c. Ligation of all purine and pyrimidine bases
d. None of the above
Answers (1)
The answer is the option (a) Formation of phosphodiester bond between two DNA fragments
Explanation: DNA ligase facilitates joining of two sticky ends of DNA fragments by formation of phosphodiester bond between them.
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