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Based on the accepted concept of hormone action, if receptor molecules are absent from target organs, what would be the correct conclusion?

 

Option: 1

The hormone will elicit a consistent response from the target organ.
 


Option: 2

The target organ will remain responsive to the hormone, but a higher concentration will be necessary to trigger a response.


Option: 3

The hormone will no longer stimulate the target organs.

 


Option: 4

The target organ's response to the hormone will be reversed or altered.


Answers (1)

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Hormones, despite being distributed throughout the bloodstream and capable of reaching all cells, only impact cells that possess specific receptors for the particular hormone. Therefore, the binding of a hormone to its corresponding receptor is crucial for the cellular response, regardless of whether the receptors are located on the cell surface or inside the cell. Given this information, options A and D are incorrect because the absence of receptors prevents the cell from being affected by the hormone. Option B is also incorrect since the binding of the hormone to its receptor is an indispensable step in hormonal activity. Hence, the correct answer is option 3.

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Pankaj

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