Based on the accepted concept of hormone action, if receptor molecules are absent from target organs, what would be the correct conclusion?
The hormone will elicit a consistent response from the target organ.
The target organ will remain responsive to the hormone, but a higher concentration will be necessary to trigger a response.
The hormone will no longer stimulate the target organs.
The target organ's response to the hormone will be reversed or altered.
Hormones, despite being distributed throughout the bloodstream and capable of reaching all cells, only impact cells that possess specific receptors for the particular hormone. Therefore, the binding of a hormone to its corresponding receptor is crucial for the cellular response, regardless of whether the receptors are located on the cell surface or inside the cell. Given this information, options A and D are incorrect because the absence of receptors prevents the cell from being affected by the hormone. Option B is also incorrect since the binding of the hormone to its receptor is an indispensable step in hormonal activity. Hence, the correct answer is option 3.