Stages of Meiosis ? - Prophase I -
Stages of Meiosis ? - Prophase I
- In meiosis I, the actual reduction in the number of chromosomes occurs.
- It starts after the homologous chromosomes have replicated during S-phase and the proteins required for division have been synthesized in G2 phase.
- Therefore, it occurs after the interphase of cell cycle.
- It is studied under Prophase I, Metaphase I, Anaphase I and Telophase I.
Prophase I
- It is the longest phase of meiosis I.
- It is divided into five substages: leptotene, zygotene, pachytene, diplotene and diakinesis.
PACHYTENE:
- The exchange of parts between non-sister chromatids occurs during this phase.
- It is called the crossing over.
- Crossing over occurs through breakage and reunion of chromatids segments.
- Breakage is called nicking. It is assisted by an enzyme endonuclease.
- Reunion termed annealing. It is aided by an enzyme ligase.

-
The exchange of parts between non-sister chromatids occurs during pachytene phase. It is called the crossing over.
View full answer