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  • Deamination of bases is a common chemical event that produces spontaneous mutation. Which one of the following bases will be formed by the deamination of 5-methylcytosine?  <div

Deamination of bases is a common chemical event that produces spontaneous mutation. Which one of the following bases will be formed by the deamination of 5-methylcytosine?

 

Option: 1

Uracil


Option: 2

Thymine


Option: 3

Cytosine


Option: 4

Guanine


Answers (1)

best_answer

Deamination of 5-methylcytosine typically results in the formation of thymine.

5-methylcytosine is a modified form of cytosine, with a methyl group attached to the 5th carbon. During deamination, the amino group (-NH2) of cytosine or its modified forms can be converted to a keto group (-O) through the removal of the amino group. This chemical reaction leads to the formation of thymine. Hence, the correct answer is option 2. 

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seema garhwal

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