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The following are some statements regarding glycolysis:
P. Glycolysis is not regulated by pyruvate kinase.
Q. Lactate can be an end product of glycolysis.
R. Glycolysis cannot function anaerobically.
S. In erythrocytes, the second site in glycolysis for ATP generation can be bypassed.
From the above, choose the combination with both incorrect statements.
P and Q
Q and S
R and S
P and R
Answers (1)
Statement P: "Glycolysis is not regulated by pyruvate kinase" is incorrect. Pyruvate kinase is indeed involved in the regulation of glycolysis. It catalyzes an important step in the pathway and its activity is regulated by various factors such as allosteric regulation and post-translational modifications.
Statement R: "Glycolysis cannot function anaerobically" is also incorrect. Glycolysis is capable of functioning anaerobically, in the absence of oxygen. In anaerobic conditions, glycolysis can proceed through fermentation, which allows for the production of ATP.
Hence, the correct answer is option 4.
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