What is the mechanism by which neurotransmitters are removed from the synaptic cleft?
Reuptake by the presynaptic neuron
Diffusion into the extracellular fluid
Uptake by glial cells
Breakdown by enzymes in the synaptic cleft
After neurotransmitters have been released into the synaptic cleft, they are removed from the cleft by a process called reuptake. The presynaptic neuron has transporter proteins on its membrane that bind to and transport the neurotransmitter back into the neuron. Once inside the neuron, the neurotransmitter can be repackaged into vesicles and used again in another transmission event.
Option 1 is the correct answer.