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When hydrogen ions bind to the hemoglobin at an allosteric site, the oxygen dissociation curve shifts to

 

Option: 1

Left

 


Option: 2

Right

 


Option: 3

Do not show any change 

 


Option: 4

First moves to left and then right

 


Answers (1)

best_answer

 

 

Bohr’s Effect on Oxygen Dissociation Curve -

  • The effect of carbon dioxide and pH on the oxygen dissociation curve is called the Bohr’s effect.
  • CO_{_{2}} is a major by-product of cellular metabolism. 
  • It is a nonpolar molecule and so it does not dissolve in the blood.
  • To increase its solubility, carbonic anhydrase converts the CO_{_{2}} into carbonic acid in the presence of water. 
  • Carbonic acid is a weak acid and it dissociates into bicarbonate and hydrogen ions that are soluble in blood.
  • As the concentration of hydrogen ions increases in the blood, the pH becomes acidic, affecting the oxygen binding with haemoglobin. 
  • Hydrogen ions bind to the haemoglobin at an allosteric site and the curve shifts to the right.
     

Hence the correct option is right 

 

Posted by

sudhir.kumar

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