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Which combination of relative values of km  (Michaelis constant) and kcat (catalytic rate constant) would indicate a high catalytic efficiency for an enzyme?

Option: 1

Low km and low kcat

 


Option: 2

High km and high kcat


Option: 3

High km and low kcat

 


Option: 4

Low km and high kcat


Answers (1)

best_answer

The combination of low km (Michaelis constant) and high kcat (catalytic rate constant) indicates a high catalytic efficiency for an enzyme.
A low km value indicates that the enzyme has a high affinity for its substrate, meaning it can effectively bind to the substrate at relatively low concentrations.
On the other hand, a high kcat value indicates that the enzyme has a high turnover rate, meaning it can efficiently convert substrate molecules into product molecules per unit time.

Hence, the correct answer is option 4. 

 

Posted by

Divya Prakash Singh

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