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Which factor or mechanism plays a significant role in the development of “Knock knee disease”?
Option: 1
Insufficiency of the essential amino acid tyrosine
Option: 2
Disruption in hormonal equilibrium
Option: 3
Excessive accumulation of fluoride in water sources
Option: 4
Genetic aberrations specifically observed in males
Answers (1)
Fluoride, when present in excessive amounts, can affect bone development and lead to skeletal abnormalities. High fluoride concentration can interfere with the normal growth and remodeling of bones, resulting in the characteristic inward curvature of the knees. Therefore, Option 3 is the correct answer.
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