Which hormone of the adenohypophysis is controlled through a feedback mechanism?
Oxytocin
TSH
Vasopressin
Cortisone
TSH is regulated by a negative feedback mechanism. When the levels of thyroid hormones (T3 and T4) in the blood decrease, the hypothalamus releases TRH(Thyroid Releasing Hormone), which stimulates the anterior pituitary gland to release TSH (Thyroid-Stimulating Hormone). TSH then acts on the thyroid gland, promoting the synthesis and release of thyroid hormones. Once the levels of thyroid hormones in the blood rise to a certain threshold, they inhibit the release of TRH and TSH through a negative feedback loop, thereby regulating their own production. This feedback mechanism helps maintain the appropriate levels of thyroid hormones in the body. Hence, the correct answer is option 2.