Which of the following enzymes does not catalyse a reversible reaction in glycolysis?
Phosphoglucoisomerase
Phosphoglycerate kinase
Pyruvate kinase
Aldolase
The last step in glycolysis is catalyzed by the enzyme pyruvate kinase and results in the production of a second ATP molecule by substrate-level phosphorylation and the compound pyruvic acid. This reaction is irreversible.
Hence, the correct option is c.